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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EEF2 All Species: 58.48
Human Site: S500 Identified Species: 98.97
UniProt: P13639 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13639 NP_001952.1 858 95338 S500 N M R V M K F S V S P V V R V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001118006 1434 155458 S1076 N M R V M K F S V S P V V R V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P58252 858 95296 S500 N M R V M K F S V S P V V R V
Rat Rattus norvegicus P05197 858 95265 S500 N M R V M K F S V S P V V R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515708 919 102141 S561 N M R V M K F S V S P V V R V
Chicken Gallus gallus Q90705 858 95360 S500 N M R V M K F S V S P V V R V
Frog Xenopus laevis NP_001080656 858 95409 S500 N M R V M K F S V S P V V R V
Zebra Danio Brachydanio rerio XP_697966 861 95866 S503 N M R V M K F S V S P V V R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13060 844 94440 S486 N M K V M K F S V S P V V R V
Honey Bee Apis mellifera XP_392691 844 94564 S486 N M K V M K F S V S P V V R V
Nematode Worm Caenorhab. elegans P29691 852 94778 S494 N M R V M K F S V S P V V R V
Sea Urchin Strong. purpuratus XP_001178871 842 94328 S484 N I K T M K F S V S P V V R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32324 842 93271 S484 N M K V M K F S V S P V V Q V
Red Bread Mold Neurospora crassa Q96X45 844 93243 S485 N M K V M K F S V S P V V Q R
Conservation
Percent
Protein Identity: 100 N.A. 59.7 N.A. N.A. 99 99.1 N.A. 92.3 97.3 95.2 92.4 N.A. 78.7 80.6 80.1 75.7
Protein Similarity: 100 N.A. 59.8 N.A. N.A. 99.5 99.6 N.A. 92.8 98.5 98.2 97.3 N.A. 86.9 87.7 88.6 85.9
P-Site Identity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 93.3 100 80
P-Site Similarity: 100 N.A. 100 N.A. N.A. 100 100 N.A. 100 100 100 100 N.A. 100 100 100 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 66.4 67.4
Protein Similarity: N.A. N.A. N.A. N.A. 78.7 80.8
P-Site Identity: N.A. N.A. N.A. N.A. 86.6 80
P-Site Similarity: N.A. N.A. N.A. N.A. 100 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 36 0 0 100 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 93 0 0 100 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % Q
% Arg: 0 0 65 0 0 0 0 0 0 0 0 0 0 86 8 % R
% Ser: 0 0 0 0 0 0 0 100 0 100 0 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 93 0 0 0 0 100 0 0 100 100 0 93 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _